Nov. 3, 2017
Biosecurity Implications for the Synthesis of Horsepox, an Orthopoxvirus
This article examines the biosecurity and biodefense implications resulting from the recent creation of horsepox virus, a noncirculating (extinct) species of orthopoxvirus. Here we examine the technical aspects of the horsepox virus synthesis and conclude that orthopox synthesis experiments currently remain technically challenging—and will continue to be so, even
once this work is published in the scientific literature.